Document and Entity Information Statement [Table] Statement [Line Items] Entity Registrant Name Entity Central Index Key Document Type Document Period End Date Amendment Flag Current Fiscal Year End Date Entity Current Reporting Status Entity Filer Category Entity Common Stock, Shares Outstanding Document Fiscal Year Focus Document Fiscal Period Focus CONSOLIDATED BALANCE SHEETS Assets [Abstract] ASSETS Assets, Current [Abstract] Current Assets: Cash and Cash Equivalents, at Carrying Value Cash and Cash Equivalents at End of Period Cash and Cash Equivalents at Beginning of Period Cash and Cash Equivalents Available-for-sale Securities, Debt Securities, Current Marketable Securities Fair Value Accounts and Other Receivables, Net, Current Accounts and Other Receivables Prepaid Expense and Other Assets, Current Prepaid and Other Current Assets Assets, Current Total Current Assets Property, Plant and Equipment, Net Property and Equipment, Net Intangible Assets, Net (Excluding Goodwill) Intangible Assets, Net Intangible Assets, Net (Excluding Goodwill) Other Assets, Noncurrent Other Assets Goodwill Goodwill Assets Total Assets Liabilities and Equity [Abstract] LIABILITIES AND STOCKHOLDERS' EQUITY Liabilities, Current [Abstract] Current Liabilities: Accounts Payable, Current Accounts Payable Accrued Liabilities, Current Accrued Expenses Other Liabilities, Current Less Current Portion Current Portion of Long-Term Liabilities Liabilities, Current Total Current Liabilities Other Liabilities, Noncurrent Other Long-Term Liabilities Long-Term Portion Liabilities Total Liabilities Commitments and Contingencies. Commitments and Contingent Liabilities Stockholders' Equity Attributable to Parent [Abstract] Stockholders' Equity: Preferred Stock, Value, Issued Convertible Preferred Stock, $.01 Par Value; 3,000,000 Shares Authorized; No Shares Issued and Outstanding at March 31, 2016 and December 31, 2015 Common Stock, Value, Issued Common Stock, $.001 Par Value; 297,000,000 Shares Authorized; 98,718,484 and 98,685,595 Shares Issued and Outstanding at March 31, 2016 and December 31, 2015, respectively Additional Paid in Capital, Common Stock Additional Paid-In Capital Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated Other Comprehensive Income Retained Earnings (Accumulated Deficit) Accumulated Deficit StockholdersEquity Balance Balance Total Stockholders' Equity Liabilities and Equity Total Liabilities and Stockholders' Equity Preferred Stock, Par or Stated Value Per Share Convertible Preferred Stock, Par Value (in dollars per share) Preferred Stock, Shares Authorized Convertible Preferred Stock, Shares Authorized Preferred Stock, Shares Issued Convertible Preferred Stock, Shares Issued Preferred Stock, Shares Outstanding Convertible Preferred Stock, Shares Outstanding Common Stock, Par or Stated Value Per Share Common Stock, Par Value (in dollars per share) Common Stock, Shares Authorized Common Stock, Shares Authorized Common Stock, Shares, Issued Common Stock, Shares Issued Common Stock, Shares, Outstanding Common Stock, Shares Outstanding CONDENSED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS Revenues [Abstract] REVENUE: This element represents revenue from product development and licensing agreements. Revenue from Product Development and Licensing Agreements Product Development and Licensing Agreements Product development and licensing agreements revenue This element represents revenue earned during the period arising from products sold or services provided under the terms of a contract. Also include revenue earned during the period from non-repayable sum of money awarded to an entity to carry out a specific purpose as provided in grant agreements. Revenue from Contracts and Grants Contracts and Grants Contracts and grants revenue Revenues Total Revenue Costs and Expenses [Abstract] OPERATING EXPENSE: Research and Development Expense Research and Development General and Administrative Expense General and Administrative Amortization of Intangible Assets Amortization of Acquired Intangible Assets Amortization of Intangible Assets Costs and Expenses Total Operating Expense Operating Income (Loss) Operating Loss Interest and Other Income Investment and Other Income, Net Net Income (Loss) Available to Common Stockholders, Basic Net Loss Net Loss Earnings Per Share, Basic and Diluted Basic and Diluted Net Loss Per Common Share (in dollars per share) Weighted Average Number of Shares Outstanding, Basic and Diluted Shares Used in Calculating Basic and Diluted Net Loss per Share (in shares) COMPREHENSIVE LOSS COMPREHENSIVE LOSS: Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Other Comprehensive Income: Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Portion Attributable to Parent Foreign Currency Translation Adjustments Other Comprehensive Income (Loss), Unrealized Holding Gain (Loss) on Securities Arising During Period, Net of Tax Unrealized Gain on Marketable Securities Comprehensive Income (Loss), Net of Tax, Attributable to Parent Comprehensive Loss CONDENSED STATEMENTS OF CASH FLOWS Net Cash Provided by (Used in) Operating Activities, Continuing Operations [Abstract] Cash Flows from Operating Activities: Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to Reconcile Net Loss to Net Cash Used in Operating Activities: Depreciation, Depletion and Amortization Depreciation and Amortization Accretion (Amortization) of Discounts and Premiums, Investments Amortization and Premium of Marketable Securities, Net Gain (Loss) on Disposition of Property Plant Equipment Loss on Sale or Disposal of Assets Share-based Compensation Stock-Based Compensation Expense Amortization of Debt Discount (Premium) Non-Cash Expense Increase (Decrease) in Operating Capital [Abstract] Changes in Operating Assets and Liabilities: Increase (Decrease) in Accounts and Other Receivables Accounts and Other Receivables Increase (Decrease) in Prepaid Expense and Other Assets Prepaid and Other Current Assets Increase (Decrease) in Other Operating Assets Other Assets Increase (Decrease) in Accounts Payable and Accrued Liabilities Accounts Payable and Accrued Expenses Increase (Decrease) in Other Operating Liabilities Other Liabilities Net Cash Provided by (Used in) Operating Activities, Continuing Operations Net cash used in operations Net Cash Used in Operating Activities Net Cash Provided by (Used in) Investing Activities, Continuing Operations [Abstract] Cash Flows from Investing Activities: Proceeds from Sale and Maturity of Marketable Securities Sales and Maturities of Marketable Securities Payments to Acquire Marketable Securities Purchases of Marketable Securities Payments to Acquire Property, Plant, and Equipment Acquisition of Property and Equipment Net Cash Provided by (Used in) Investing Activities, Continuing Operations Net Cash Provided by (Used in) Investing Activities Net Cash Provided by (Used in) Financing Activities, Continuing Operations [Abstract] Cash Flows from Financing Activities: Proceeds from Issuance of Common Stock Net Proceeds from Stock Issuances Proceeds from Stock Plans Proceeds from Issuance of Stock from Employee Benefit Plans Net Cash Provided by (Used in) Financing Activities, Continuing Operations Net Cash Provided by Financing Activities Effect of Exchange Rate on Cash and Cash Equivalents, Continuing Operations Effect of Exchange Rate Changes on Cash and Cash Equivalents Cash and Cash Equivalents, Period Increase (Decrease) Net (Decrease) Increase in Cash and Cash Equivalents Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Non-cash Investing Activities Capital Expenditures Incurred but Not yet Paid Acquisition of Property and Equipment included in Accounts Payable and Accrued Expenses Basis of Presentation Basis of Accounting [Text Block] BASIS OF PRESENTATION SIGNIFICANT ACCOUNTING POLICIES Significant Accounting Policies [Text Block] SIGNIFICANT ACCOUNTING POLICIES Net Loss Per Share Earnings Per Share [Text Block] NET LOSS PER SHARE Comprehensive Income (Loss) Note [Text Block] COMPREHENSIVE LOSS FAIR VALUE MEASUREMENTS. Fair Value Disclosures [Text Block] FAIR VALUE MEASUREMENTS MARKETABLE SECURITIES Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block] MARKETABLE SECURITIES INTANGIBLE ASSETS AND GOODWILL Goodwill and Intangible Assets Disclosure [Text Block] INTANGIBLE ASSETS AND GOODWILL OTHER LONG-TERM LIABILITIES Other Liabilities Disclosure [Text Block] OTHER LONG-TERM LIABILITIES STOCKHOLDERS' EQUITY Stockholders' Equity Note Disclosure [Text Block] STOCKHOLDERS' EQUITY STOCK-BASED COMPENSATION Disclosure of Compensation Related Costs, Share-based Payments [Text Block] STOCK-BASED COMPENSATION REVENUE. This element may be used to capture the complete disclosure pertaining to an entity's significant revenue contracts and arrangements. Significant Revenue Arrangements Disclosure [Text Block] REVENUE INCOME TAXES Income Tax Disclosure [Text Block] INCOME TAXES SUBSEQUENT EVENT Subsequent Events [Text Block] SUBSEQUENT EVENT New Accounting Pronouncements, Policy [Policy Text Block] Recent Accounting Pronouncements Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Schedule of potentially dilutive common shares that have not been included in the net loss per common share calculations because the effect would have been anti-dilutive Schedule of Accumulated Other Comprehensive Income (Loss) [Table Text Block] Summary of changes in accumulated other comprehensive income (loss) by component Fair Value, Assets Measured on Recurring Basis [Table Text Block] Schedule of financial assets subject to fair value measurements Schedule of Available-for-sale Securities Reconciliation [Table Text Block] Summary of marketable securities Schedule of Intangible Assets and Goodwill [Table Text Block] Schedule of intangible assets, net of accumulated amortization, and goodwill Tabular disclosure of other long-term liabilities, not separately disclosed on the balance sheet. Schedule of Other Long Term Liabilities [Table Text Block] Schedule of other long-term liabilities Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block] Summary of stock option activity Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block] Schedule of stock-based compensation expense Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Schedule of assumptions used for the fair values of employee stock options granted Investments and Cash Cash, cash equivalents and marketable securities Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Antidilutive Securities [Axis] Antidilutive Securities Name [Domain] Antidilutive Securities, Name [Domain] An arrangement whereby an employee, consultant or non-employee director is entitled to receive in the future, subject to vesting and other restrictions, a number of shares in the entity at a specified price, as defined in the agreement. Although there are variations, normally, after vesting, when an option is exercised, the holder pays the strike value in cash to the issuing entity and receives equity shares. The equity shares can be sold into the market for cash at the current market price without restriction. Options may be used to attract, retain and incentivize recipients, in addition to other compensation and other benefits, if any. Employee Consultant And Non Employee Director Stock Option [Member] Stock options Restricted Stock [Member] Restricted stock Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Anti-dilutive securities Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Potentially dilutive common shares that have not been included in the net loss per common share calculations because the effect would have been anti-dilutive Accumulated Other Comprehensive Income (Loss) [Table] Equity Components [Axis] Equity Component [Domain] Equity Component [Domain] Accumulated Net Unrealized Investment Gain Loss [Member] Unrealized Gain (Loss) on Marketable Securities Accumulated Translation Adjustment [Member] Foreign Currency Items Accumulated Other Comprehensive Income (Loss) [Line Items] Comprehensive Income Accumulated Other Comprehensive Income (Loss) [Roll Forward] Changes in accumulated other comprehensive income (loss) by component Other Comprehensive Income (Loss), before Reclassifications, Net of Tax Other comprehensive income before reclassifications Reclassification from Accumulated Other Comprehensive Income, Current Period, Net of Tax Amounts reclassified out of accumulated other comprehensive income Other Comprehensive Income (Loss), Net of Tax Net current-period other comprehensive income Fair Value Measurements, Recurring and Nonrecurring [Table] Measurement Frequency [Axis] Fair Value Measurement Frequency [Domain] Fair Value, Measurement Frequency [Domain] Fair Value Measurements Recurring [Member] Fair Value Measurements Fair Value, Hierarchy [Axis] Fair Value Measurements Fair Value Hierarchy [Domain] Fair Value Hierarchy [Domain] Fair Value Inputs Level2 [Member] Level 2 Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair value measurements Cash and Cash Equivalents, Fair Value Disclosure Money market funds and cash equivalents Available-for-sale Securities Marketable securities Assets, Fair Value Disclosure Total financial assets at fair value Represents the amount of transfer of assets measured on a recurring basis between Level 1, Level 2 and Level 3 of the fair value hierarchy. Fair Value Assets Amount Transfers between Measurement Levels Assets transferred between the fair value measurement classifications Represents the amount of transfer of liabilities measured on a recurring basis between Level 1, Level 2 and Level 3 of the fair value hierarchy. Fair Value Liabilities Amount Transfers between Measurement Levels Liabilities transferred between the fair value measurement classifications Schedule of Available-for-sale Securities [Table] Major Types of Debt and Equity Securities [Axis] Major Types Of Debt And Equity Securities [Domain] Major Types of Debt and Equity Securities [Domain] Represents securities issued by US government agencies and municipal governments. U S Government And Municipal Obligations [Member] U.S. government and municipal obligations Corporate Debt Securities [Member] Corporate debt securities Schedule of Available-for-sale Securities [Line Items] Marketable Securities Available-for-sale Securities, Debt Maturities, Amortized Cost Basis, Fiscal Year Maturity [Abstract] Amortized Cost Available-for-sale Securities, Debt Maturities, Next Twelve Months, Amortized Cost Basis Maturing in one year or less Amount of available-for-sale debt securities at cost, net of adjustments, maturing in the second fiscal year through the third fiscal year following the latest fiscal year. Available For Sale Securities, Debt Maturities after One Through Three Years, Amortized Cost Maturing after one year through three years Available-for-sale Debt Securities, Amortized Cost Basis Amortized cost Available-for-sale Securities, Gross Unrealized Gain [Abstract] Gross Unrealized Gains Represents the gross unrealized gains on securities, at a point in time, for those securities which are expected to mature within one year of the balance sheet date, and which are categorized neither as held-to-maturity nor as trading securities. Available For Sale Securities, Debt Maturities within One Year Gross Unrealized Gain Maturing in one year or less Represents the gross unrealized gains on securities, at a point in time, for those securities which are expected to mature after one year and through three years from the balance sheet date, and which are categorized neither as held-to-maturity nor as trading securities. Available For Sale Securities, Debt Maturities after One Through Three Years, Gross Unrealized Gain Maturing after one year through three years AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax Gross Unrealized Gains Available For Sale Securities, Gross Unrealized Losses [Abstract] Gross Unrealized Losses Represents the gross unrealized losses on securities, at a point in time, which are expected to mature within one year of the balance sheet date, and which are categorized neither as held-to-maturity nor as trading securities. Available For Sale Securities, Debt Maturities within One Year, Gross Unrealized Losses Maturing in one year or less Represents the gross unrealized losses on securities, at a point in time, which are expected to mature after one year and through three years from the balance sheet date, and which are categorized neither as held-to-maturity nor as trading securities. Available For Sale Securities, Debt Maturities after One Through Three Years, Gross Unrealized Losses Maturing after one year through three years AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax Gross Unrealized Losses Available-for-sale Securities, Debt Maturities, Fair Value, Fiscal Year Maturity [Abstract] Fair Value Available-for-sale Securities, Debt Maturities, Next Twelve Months, Fair Value Maturing in one year or less Amount of available-for-sale debt securities at fair value maturing in the second fiscal year through the third fiscal year following the latest fiscal year. Available For Sale Securities, Debt Maturities after One Through Three Years, Fair Value Maturing after one year through three years Represents the amount of investment in debt and equity securities considered to be other-than-temporarily impaired, categorized neither as held-to-maturity nor trading. Available For Sale Securities, Considered to be Other than Temporarily Impaired Marketable securities considered to be other-than-temporarily impaired Interest Receivable Accrued interest included in marketable securities Disclosure of the carrying value of purchased amortizable finite-lived intangible assets, including disclosure of the carrying value of indefinite-lived intangible assets not subject to amortization, excluding goodwill, in total and by major class. Finite Lived and Indefinite Lived Intangible Assets by Major Class [Table] Indefinite-lived Intangible Assets [Axis] Indefinite Lived Intangible Assets Major Class Name [Domain] Indefinite-lived Intangible Assets, Major Class Name [Domain] In Process Research And Development [Member] IPR&D Finite-Lived Intangible Assets by Major Class [Axis] Finite Lived Intangible Assets Major Class Name [Domain] Finite-Lived Intangible Assets, Major Class Name [Domain] Represents information pertaining to an amendment to the license agreement, Amgen Amendment. Amgen Amendment [Member] Amgen Amendment Represents information pertaining to the core technology of the entity. Core Technology [Member] Core Technology Finite Lived and Indefinite Lived Intangible Assets by Major Class [Line Items] Intangible Assets and Goodwill Indefinite-Lived Intangible Assets (Excluding Goodwill) [Abstract] Indefinite-lived intangible assets: Indefinite-Lived Intangible Assets (Excluding Goodwill) Indefinite-lived intangible assets Finite-Lived Intangible Assets, Net [Abstract] Finite-lived intangible asset Finite-Lived Intangible Asset, Useful Life Estimated Life Finite-Lived Intangible Assets, Gross Cost Finite-Lived Intangible Assets, Accumulated Amortization Accumulated Amortization Finite-Lived Intangible Assets, Net Net Intangible Assets, Net (Excluding Goodwill) [Abstract] Total Intangible Assets Intangible Assets, Gross (Excluding Goodwill) Cost of total intangible assets Deferred Rent Credit Deferred Rent Deferred Income Tax Liabilities, Net Net Deferred Tax Liability related to IPR&D Represents the deferred income from the sale of tax benefit. Deferred Income from Sale of Tax Benefits Deferred Income from Sale of Tax Benefits Deferred Revenue Deferred Revenue Other Liabilities Total Represents the value of tax benefits agreed to be sold by the entity during the reporting period. Value of Tax Benefits Agreed to be Sold Amount at which New Jersey tax benefit agreed to be sold Represents the value at which tax benefit sold by the entity during the reporting period. Value at which Tax Benefits Sold Amount of sale of New Jersey tax benefit Represents period for which base of operations must be maintained in New Jersey. Period for which Base of Operations Must be Maintained Period for which base of operations must be maintained Gain (Loss) on Disposition of Other Assets Other income related to sale of tax benefits Disclosure of information pertaining to changes in stockholders' equity during the period. Stockholders Equity [Table] Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. Stockholders Equity [Line Items] Stockholders' Equity Stock Issued During Period, Shares, New Issues Common stock issued (in shares) Stock Issued During Period, Shares, New Issues. Net proceeds from sale of stock in an underwritten public offering Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Award Type [Axis] Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain] Equity Award [Domain] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Stock-Based Compensation Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward] Shares Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Number Options Outstanding at the end of the period (in shares) Options Outstanding at beginning of the period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Gross Granted (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period Exercised (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Forfeitures in Period Canceled (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Options Vested and Expected to Vest at the end of the period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Number Options Exercisable at the end of the period (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Number of Shares Available for Grant Shares Available for Grant under the 2008 Plan (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Weighted Average Exercise Price Per Share Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price Options Outstanding at the end of the period (in dollars per share) Options Outstanding at beginning of the period (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Granted (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Exercised (in dollars per share) Share-based Compensation Arrangements by Share-based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Canceled (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Options Vested and Expected to Vest at the end of the period (in dollars per share) Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Exercise Price Options Exercisable at the end of the period (in dollars per share) Share Based Compensation Arrangement by Share Based Payment Award, Options, Weighted Average Remaining Contractual Term [Abstract] Weighted Average Remaining Contractual Term Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Options Outstanding at the beginning of the period Options Outstanding at the end of the period Share-based Compensation Arrangement by Share-based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Remaining Contractual Term Options Vested and Expected to Vest at the end of the period Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Options Exercisable at the end of the period Share-based Compensation Arrangement by Share-based Payment Award, Additional General Disclosures [Abstract] Additional information Share-based Compensation Arrangement by Share-based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Weighted average grant-date fair value (in dollars per share) Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table] Income Statement Location [Axis] Income Statement Location [Domain] Income Statement Location [Domain] Research And Development Expense [Member] Research and development General And Administrative Expense [Member] General and administrative Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items] Valuation and Expenses Information Allocated Share-based Compensation Expense Total stock-based compensation expense (in dollars) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions and Methodology [Abstract] Assumptions used for fair values of employee and director stock options granted Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Volatility Rate Expected stock price volatility (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Term Expected option term Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Risk Free Interest Rate Risk-free interest rate (as a percent) Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Rate Expected dividend yield (as a percent) Schedule of Collaborative Arrangements and Non-collaborative Arrangement Transactions [Table] Products and Services [Axis] Products And Services [Domain] Products and Services [Domain] Represents the information pertaining to the product PD-1 immune checkpoint inhibitor. Pd1 Immune Checkpoint Inhibitor [Member] PD-1 Immune Checkpoint Inhibitor Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] REVENUE Represents the term of the collaborative arrangement. Collaborative Arrangement Agreement Term Term of the agreement Represents percentage of reimbursement of external costs incurred by the company. Reimbursement of external costs incurred percentage Reimbursement of external costs incurred by the company (as a percent) Number of States in which Entity Operates Number of states in which the entity primarily operates or has operated and has income tax nexus Subsequent Event [Line Items] Subsequent Event Represents the cash outflow to enter into a research and collaboration agreement with a company to access novel technologies and make an investment in the company. Payment For Research And Collaboration Agreement And Investment In Company Payment for research and collaboration agreement and investment in company Accumulated Other Comprehensive Income [Member] Accumulated Other Comprehensive Income Measurement Basis [Axis] Portion At Fair Value Fair Value Disclosure [Member] Portion at Fair Value Measurement [Member] Estimate Of Fair Value Fair Value Disclosure [Member] Fair value Sale of Stock [Axis] Sale Of Stock Name Of Transaction [Domain] Sale of Stock [Domain] Represents details about an underwritten public offering. Underwritten Public Offering [Member] Underwritten Public Offering Counterparty Name [Axis] Repurchase Agreement Counterparty Name [Domain] Counterparty Name [Domain] Represents information related to Bristol Meyers Squibb Company. Bristol Meyers Squibb Company [Member] BMS Represents information related to Rockefeller University. Rockefeller University [Member] Rockefeller Subsequent Event Type [Axis] Subsequent Event Type [Domain] Subsequent Event Type [Domain] Subsequent Event [Member] Subsequent Event