Celldex Announces Upcoming Presentation of CDX-0159 Phase 1b Results in Inducible Urticaria at the 2021 European Academy of Dermatology and Venereology (EADV) 30th Congress
|Presentation #P0368:||CDX-0159, an anti-KIT antibody, demonstrates rapid and sustained clinical response and improved quality of life in patients with chronic inducible urticaria|
|Date:||Pre-recorded poster discussion available on demand from
|Session type:||Electronic poster|
|Session Category:||Biologics, immunotherapy, targeted therapy|
Interim data included in the abstract were current as of the time of submission in May; updated results will be presented at EADV.
CDX-0159 is a humanized monoclonal antibody that specifically binds the receptor tyrosine kinase KIT with high specificity and potently inhibits its activity. KIT is expressed in a variety of cells, including mast cells, which mediate inflammatory responses such as hypersensitivity and allergic reactions. KIT signaling controls the differentiation, tissue recruitment, survival and activity of mast cells. In certain inflammatory diseases, such as chronic urticaria, mast cell activation plays a central role in the onset and progression of the disease.
Celldex is a clinical stage biotechnology company dedicated to developing monoclonal and bispecific antibodies that address devastating diseases for which available treatments are inadequate. Our pipeline includes antibody-based therapeutics which have the ability to engage the human immune system and/or directly affect critical pathways to improve the lives of patients with inflammatory diseases and many forms of cancer. Visit www.celldex.com.
Forward Looking Statement
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Senior Vice President, Corporate Affairs & Administration
Senior Director, Investor Relations & Corporate Communications
Source: Celldex Therapeutics, Inc.